25 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12/02/1964 | H | Georgetown College | W | 81 | 74 | 1-0 | 0-0 | 4,929 | Louisville | Ky. | Freedom Hall | ||||
| 12/05/1964 | A | Marquette | W | 73 | 60 | 2-0 | 0-0 | ||||||||
| 12/12/1964 | A | Cincinnati | L | 57 | 67 | 2-1 | 0-1 | ||||||||
| 12/16/1964 | H | Syracuse | W | 67 | 62 | 3-1 | 0-1 | 6,960 | Louisville | Ky. | Freedom Hall | ||||
| 12/19/1964 | H | DePaul | W | 70 | 69 | 4-1 | 0-1 | 5,109 | Louisville | Ky. | Freedom Hall | ||||
| 12/23/1964 | H | Bellarmine | W | 88 | 71 | 5-1 | 0-1 | 10,419 | Louisville | Ky. | Freedom Hall | ||||
| 12/26/1964 | A | Bradley | W | 82 | 74 | 6-1 | 1-1 | ||||||||
| 12/29/1964 | N | Georgia Tech | W | 77 | 71 | 7-1 | 1-1 | New Orleans | La. | 1964 Sugar Bowl Tournament | |||||
| 12/30/1964 | N | Vanderbilt | L | 47 | 80 | 7-2 | 1-1 | New Orleans | La. | 1964 Sugar Bowl Tournament | |||||
| 01/04/1965 | H | Drake | W | 76 | 64 | 8-2 | 2-1 | 5,502 | Louisville | Ky. | Freedom Hall | ||||
| 01/06/1965 | H | La Salle | W | 92 | 80 | 9-2 | 2-1 | 7,122 | Louisville | Ky. | Freedom Hall | ||||
| 01/09/1965 | A | Tulsa | L | 62 | 76 | 9-3 | 2-2 | 2,300 | Tulsa | Okla. | Tulsa Fairgrounds Pavilion | ||||
| 01/11/1965 | A | North Texas State | W | 70 | 68 | OT | 10-3 | 3-2 | Denton | Texas | |||||
| 01/16/1965 | H | Georgia Tech | L | 63 | 66 | 10-4 | 3-2 | 5,248 | Louisville | Ky. | Louisville Convention Center | ||||
| 01/19/1965 | H | Cincinnati | W | 82 | 80 | 3OT | 11-4 | 4-2 | 9,816 | Louisville | Ky. | Freedom Hall | |||
| 01/23/1965 | A | Dayton | L | 78 | 83 | 11-5 | 4-2 | ||||||||
| 01/30/1965 | A | 5 | Wichita State | L | 76 | 96 | 11-6 | 4-3 | |||||||
| 02/04/1965 | H | Tulsa | W | 73 | 67 | 12-6 | 5-3 | 5,375 | Louisville | Ky. | Louisville Convention Center | ||||
| 02/06/1965 | H | North Texas State | W | 98 | 72 | 13-6 | 6-3 | 5,614 | Louisville | Ky. | Louisville Convention Center | ||||
| 02/13/1965 | H | Bradley | W | 80 | 78 | 14-6 | 7-3 | 13,336 | Louisville | Ky. | Freedom Hall | ||||
| 02/17/1965 | H | Saint Louis | L | 63 | 70 | 14-7 | 7-4 | 9,780 | Louisville | Ky. | Freedom Hall | ||||
| 02/20/1965 | A | Drake | L | 65 | 84 | 14-8 | 7-5 | Des Moines | Iowa | Veterans Memorial Auditorium | |||||
| 02/24/1965 | H | Dayton | L | 70 | 75 | 14-9 | 7-5 | 8,802 | Louisville | Ky. | Freedom Hall | ||||
| 02/27/1965 | A | Saint Louis | L | 65 | 78 | 14-10 | 7-6 | ||||||||
| 03/03/1965 | H | Wichita State | W | 79 | 70 | 15-10 | 8-6 | 11,153 | Louisville | Ky. | Freedom Hall |